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Sickle cell retinopathy molecular investigation through proteomic analysis of Townes HbSS mice retinas

paper
Psi experiments and remote viewingJúlia Nicoliello Pereira de Castro, Ana Rafaela Carvalho Monte, Ana Carolina Rodrigues de Oliveira, Julia Dezordi Acacio, Thiago Adalton Rosa Rodrigues, Mirella Telles Salgueiro Barboni, André MauríciOctober 14, 2026
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Parapsychology

Sickle cell retinopathy (SCR) is the most important ocular manifestation in sickle cell disease (SCD). Retinal tissue is highly sensible to vaso-occlusion and hypoxia observed in SCR pathophysiology, with consequent vessel remodeling and ultimately neovascularization in its proliferative form. Severe cases are followed by vitreous hemorrhage and retinal detachment, with 10–20% of vision loss in affected eyes. Current treatment options such as anti-VEGF (Vascular Endothelial Growth Factor) injections and laser photocoagulation are based on other proliferative retinopathies, without pre-clinical

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  1. Stroboscopic light stimulation safety within and beyond laboratory settings: Observational evidence and practical guidance

    paper
    Psi experiments and remote viewingDavid John Schwartzman, Trevor Hewitt, Timo Torsten Schmidt, Josemir Wanderley Sander, Danny Nacker, James Thurbon, Vince Polito, Xaver Funk, et al.October 14, 2026

    Stroboscopic light stimulation (SLS) reliably evokes geometric visual hallucinations and, in some contexts, altered-state experiences. Its increasing use in research, public, recreational and exploratory clinical settings creates a need for proportionate safety guidance. The main concern is a visually triggered seizure in a susceptible individual; reported non-epileptic responses include discomfort or distress. We combined a retrospective survey of safety practices and reported events across four laboratories, provider-reported operational data from two commercial SLS platforms, and a focused

    Original source ↗Parapsychology

  2. Genetically modified cones rescue visual function in children

    paper
    Psi experiments and remote viewingRoni O. Maimon-Mor, Mahtab Farahbakhsh, Andrew T. Rider, Andrew Stockman A, Teo Berthy-Parker, Mohamed Katta, Michel Michaelides, Tessa M. DekkerOctober 14, 2026

    Gene therapy can restore retinal signals absent since birth in animal models, yet the translation to humans remains challenging. An unresolved possibility is that meaningful retinal rescue already occurs in humans, but its impact is masked by downstream neural bottlenecks shaped by long-term deprivation. Tracing restored signals through the visual system is therefore essential to distinguish rescue and constraints. We address this challenge in CNGA3-associated achromatopsia, in which retinal cone photoreceptors are present but non-functional from birth. We used tests specifically targeting con

    Original source ↗Parapsychology

  3. Biophotonic Signaling in Energetic Biocommunication: A Conceptual Framework and Experimental Strategy for Validating Weak Optical Interactions in Biofields

    paper
    Psi experiments and remote viewingRick SáOctober 15, 2026

    Ultraweak photon emissions (UPEs) represent a plausible yet underexplored biophysical mechanism underlying energetic biocommunication between human organisms, particularly in the context of biofield therapies (BTs) such as Reiki, Therapeutic Touch, and External Qigong. Although biophotonic emission is a well-documented property of living systems across all kingdoms of life, the present perspective focuses specifically on the human organism as a photoinformatic system. The central methodological gap obstructing empirical validation lies in the inability to simultaneously detect UPEs from a huma

    Original source ↗Parapsychology

  4. The Near-Death Experience, an Instance of Higher-Dimensional Phenomenal Consciousness?

    paper
    Near-death experiences — title watchPekka RechardtSeptember 29, 2026

    Phenomenal consciousness has no satisfactory explanation in the strict natural scientific physicalist framework. This may be an indication of consciousness not being a causal outcome of neurophysics at all. If this is the case, there would be no grounds for postulating that the collapse of neurophysical structures at death would dissolve consciousness and its constituent elements. If consciousness does not disappear when neurophysical functions terminate, the near-death experience could be an indication of the continuation of consciousness after the collapse of brain functions. This would be i

    Original source ↗Consciousness & philosophyParapsychology

  8. "Near-death experience is completely real; it helped to understand the separation between experiential paths and the brain's own invented paths in many things. Whoever does not experience it, it is hard for them to understand."

    paper
    Near-death experience research, Near-death experiences — title watchRisto SilvennoinenOctober 11, 2026

    The final narratives so that you understand what our brains can do, ( NDE) is not connected to quantum entanglement , death is always death when our biological machine shuts down and time travel that is up to you how you interpret :)

    Original source ↗Parapsychology

  9. The Leviathan's Reckoning

    paper
    Near-death experience researchMingze GaoOctober 14, 2026

    Set in 1847 during the peak of the North Atlantic whaling industry, The Leviathan's Reckoning presents a poignant narrative of human greed, moral tension, and nature's retribution. Driven by an insatiable hunger for whale oil profit, Captain Fred Winston of the brig Sea Serpent ignores an elderly fisherman's stern warnings regarding the cursed waters of Death Valley, going so far as ordering the innocent man's demise to protect his commercial interests. Aboard the ship are two young boys — the captain's introspective son, Johnny, and a trapped orphan, Banner — both of whom harbour a deep avers

    Original source ↗Parapsychology

  10. Impact of event scale-revised-defined early psychological stress and 90-day outcomes in septic shock survivors

    paper
    Near-death experience researchLin Chai, Xiao-Yu Liu, Ming Luo, Peng-Fei Liang, Ying-Ming Li, Ling Li, Shu-Bin GuoOctober 14, 2026

    BACKGROUNDSeptic shock is associated with high mortality and substantial long-term morbidity.Survivors may experience early trauma-related stress symptoms, anxiety, and depression during recovery.In this study, psychological stress was operationalized as screening positivity on the Impact of Event Scale-Revised (IES-R), not as a formal diagnosis of acute stress disorder or post-traumatic stress disorder.We evaluated the prevalence of IES-Rdefined early psychological stress, its associations with illness severity and 90-day outcomes, and an exploratory multivariable association model in septic

    Original source ↗Parapsychology

  11. Longitudinal relationships between anxiety and fear of progression in post-CABG patients: a cross-sectional and cross-lagged panel network analysis

    paper
    Near-death experience researchZhengwei Luo, Fenghui Chen, Huihui Li, Weilong Wang, Duohuan Chen, Guo Yongzhong, Juan Xing, Fang Liang, et al.October 14, 2026

    Background Patients following coronary artery bypass grafting (CABG) frequently experience elevated anxiety and fear of progression (FoP), which has a high comorbidity and significantly increases adverse postoperative event risks. This prospective study explored the dynamic longitudinal associations between anxiety and FoP in post-CABG patients using network analysis methods. Methods A prospective longitudinal design enrolled first-time CABG patients from three tertiary hospitals in Urumqi, China. Anxiety and FoP were assessed using the Generalized Anxiety Disorder-7 (GAD-7) and the Fear of Pr

    Original source ↗Parapsychology

  12. African American Hope for Russian Culture? Feminist Ambitions and Racial Ambivalence in Evgeniia Nekrasova’s Skin

    paper
    Near-death experience researchIrina V. Anisimova, Dinara YangeldinaOctober 15, 2026

    Abstract This article examines Evgeniia Nekrasova’s Skin ( Kozha , 2021) by situating the novel within key transformations in 2020s Russian culture, particularly within the rise of feminist discourses and digital literary experimentation. Through a close reading of the novel’s narrative structure, language experiments, and reception, this article analyzes the device of skin exchange between a Russian serf and an enslaved African American woman as a metaphor for cultural transformation and equivalence. It argues that the novel mobilizes African American women’s literature as a powerful model, p

    Original source ↗Parapsychology